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Escaline Hydrochloride

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Escaline hydrochloride properties

Synonym:3,5-dimethoxy-4-ethoxyphenethylamine hydrochloride
CAS Number:39201-82-6
Formula:2-{3,5-dimethoxy-4-ethyloxyphenyl}ethan-1-amine hydrochloride
Mole mass:261.8 g/mol
Purity:>97%

Description

Escaline Hydrochloride — Specifications, Profile & Verified Sourcing Guide

What Is Escaline Hydrochloride and Why Researchers Choose Ethoxy-Substituted Phenethylamine Reference Salt

If you are searching for a precisely characterized, independently verified phenethylamine analog carrying an ethoxy group at the 4-position of the benzene ring and presented as a stable hydrochloride salt, Escaline Hydrochloride stands among the most valuable reference compounds available to modern neuroscience, pharmacology, and structure-activity relationship research. Buy Escaline Hydrochloride, and you obtain a compound whose receptor binding affinity, metabolic stability, solubility profile, and pharmacological duration differ measurably from mescaline, proscaline, and other alkoxy-substituted phenethylamine analogs, as well as from free base or alternative salt forms of escaline itself. Researchers frequently ask what exactly Escaline Hydrochloride is, how it differs from mescaline, other alkoxy-substituted phenethylamine variants, and non-hydrochloride forms, what its mechanism of action and potency values are, where to order authentic Escaline Hydrochloride online, and how to purchase Escaline Hydrochloride securely using bitcoin. This comprehensive guide answers all those questions, provides fully verified specifications including hydrochloride salt properties, explains pharmacological profile, solubility advantages, and research significance, and offers practical guidance for sourcing authentic material and purchasing with cryptocurrency.
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Escaline Hydrochloride: chemical structure

Escaline Hydrochloride combines the well-defined 3,5-dimethoxy phenethylamine backbone with a 4-ethoxy substitution—a linear two-carbon alkoxy side chain that creates a predictable structural intermediate between the 4-methoxy group of Mescaline and the 4-propoxy group of Proscaline—presented as the hydrochloride salt for improved stability, water solubility, and consistent dosing. This specific structural modification—extending the 4-position alkoxy chain length from one carbon to two carbons—profoundly alters receptor binding affinity, metabolic stability, and functional potency compared to mescaline, while the hydrochloride counterion further modifies physical properties without altering the active molecule’s intrinsic pharmacological activity. Order Escaline Hydrochloride from trusted suppliers and receive material whose identity matches authoritative reference data, because mislabeled alkoxy-substituted phenethylamines or incorrect salt forms produce irreproducible results and misleading potency values. This combination of well-defined ethoxy substitution, confirmed hydrochloride salt identity, improved metabolic stability, and distinctive solubility is why researchers choose to buy Escaline Hydrochloride using bitcoin for private, borderless transactions and reliably consistent reference material. You can independently verify the active compound through authoritative public chemical databases, including the comprehensive entry at Escaline CAS 54851-35-1 chemical reference maintained by the U.S. National Institutes of Health.

Full Specifications, Hydrochloride Salt Properties, and Research Significance

Verified Composition, Physical Properties, and Quality Standards

Before you buy Escaline Hydrochloride, you should always confirm the basic specifications to ensure you are receiving an authentic, accurately identified product in the correct salt form. The active compound Escaline carries CAS registry number 54851-35-1, molecular formula C₁₁H₁₇NO₃ (free base), while the hydrochloride salt has molecular formula C₁₁H₁₇NO₃·HCl and molecular weight 247.72 grams per mole. Premium-grade Escaline Hydrochloride should meet or exceed 98% total purity as measured by high-performance liquid chromatography, with identity confirmed by nuclear magnetic resonance spectroscopy verifying both the ethoxy substitution pattern and the presence of the hydrochloride counterion, and mass spectrometry matching the free-base molecular weight alongside independent salt verification. Authentic hydrochloride salt appears as a white to off-white crystalline or microcrystalline powder, free from visible impurities, discoloration, or clumping, and typically exhibits characteristic solubility behavior and melting properties that distinguish it from mescaline hydrochloride, proscaline hydrochloride, and free base escaline. When you compare suppliers seeking the best price for Escaline Hydrochloride payable with bitcoin, remember that authentic Escaline synthesis requires controlled O-alkylation with ethyl halide, rigorous purification, and then controlled salt formation with hydrochloric acid to achieve the correct stoichiometry and physical properties. Prices that appear unreasonably low may indicate impure material, incorrect alkoxy chain length, mescaline or proscaline sold incorrectly as escaline, wrong salt form, degraded product, or lack of independent batch verification. Always cross-reference specifications against independently verified regulatory and chemical records, including the detailed substance profile at Escaline ECHA substance information provided by the European Chemicals Agency, before making any purchase decision.
Structurally, escaline hydrochloride differs from mescaline by the replacement of the 4-methoxy group with an ethoxy group—a linear two-carbon chain extension that profoundly enhances receptor affinity and potency—while the hydrochloride counter-ion further modifies physical properties, including aqueous solubility and dissolution rate, without altering the active molecule’s pharmacological mechanism. Compared to free base form, escaline hydrochloride dissolves more readily in aqueous buffer solutions and forms a crystalline solid that typically exhibits improved long-term storage stability and consistent gravimetric dosing characteristics. These differences make escaline hydrochloride uniquely valuable not only for comparative potency studies but also for structure-activity relationship research examining exactly how incremental alkoxy chain-length extension alters biological activity independently from other structural changes. Order Escaline Hydrochloride with verified ethoxy substitution and confirmed hydrochloride salt identity, and you eliminate two major confounding variables—structural verification and salt-form uniformity—that complicate research using mislabeled analogs, free base material, or unspecified salt forms. This structural clarity and formulation consistency is why researchers prefer to order Escaline Hydrochloride using bitcoin—paying with cryptocurrency ensures fast settlement, enhanced privacy, and global accessibility, while a well-characterized hydrochloride salt eliminates formulation variability and simplifies comparative studies across the entire alkoxy-substituted phenethylamine series.
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Escaline Hydrochloride: 3D representation

Receptor Binding Profile, Comparative Potency, and Salt-Form Advantages

At the molecular level, escaline hydrochloride functions primarily as a potent serotonin 5-HT₂A receptor agonist with measurable activity at related 5-HT₂ subtypes and substantially lower affinity at other monoamine receptors. Published structure-activity data confirm that extending the 4-alkoxy chain length from methoxy through ethoxy to propoxy produces a progressive increase in 5-HT₂A receptor affinity and functional potency—with Escaline occupying the well-defined middle position between Mescaline and Proscaline, making it the essential reference point for quantifying exactly how each additional carbon atom in the alkoxy chain alters receptor interactions and biological activity. The hydrochloride salt form offers distinct advantages: excellent aqueous solubility, consistent dissolution profile across physiological pH conditions, well-characterized crystalline structure that simplifies accurate gravimetric dosing and stock solution preparation, and lower hygroscopicity than some alternative salt forms. Importantly, the hydrochloride counterion dissociates completely in solution and does not alter receptor binding affinity or functional potency—meaning all pharmacological activity derives from the Escaline cation itself, making Escaline Hydrochloride directly comparable to other salt forms and other alkoxy analogs when calculated on a molar free-base basis. What makes Escaline Hydrochloride uniquely valuable beyond its potency is its dual reference role: it serves both as the benchmark ethoxy-substituted compound for quantifying linear chain-length effects and as a standard reference hydrochloride salt for evaluating how counter-ion selection alters physical properties and formulation behavior without changing pharmacological activity.
Researchers specifically seeking verified ethoxy reference material in hydrochloride salt form should buy authentic Escaline Hydrochloride whose identity has been confirmed by NMR spectroscopy capable of verifying both the ethoxy substitution pattern and distinguishing it from longer or shorter alkoxy variants—because mass spectrometry alone cannot reliably distinguish Escaline from Mescaline or Proscaline when molecular weight differences are small, nor can it identify which salt form is present. Many suppliers sell mislabeled material, incorrect chain-length analogs, or free base incorrectly marketed as the hydrochloride form; verify both substitution pattern and salt identity before releasing payment. That distinction is why Escaline Hydrochloride serves as such an invaluable reference tool: it allows researchers to isolate exactly how each incremental alkoxy chain extension alters biological activity and separately how salt-form selection alters physical properties—all from the same verified compound within a well-characterized homologous series. Additional authoritative reference data on phenethylamine receptor interactions and classification can be reviewed at PubChem phenethylamine analog classification and PubMed Escaline research literature to further validate every specification and pharmacological property.
When you compare escaline hydrochloride against mescaline hydrochloride, proscaline hydrochloride, and escaline free base, its advantages become clear. Mescaline hydrochloride is well-characterized but exhibits low receptor affinity and rapid metabolism. Proscaline Hydrochloride offers higher potency but lacks the intermediate chain-length reference value that Escaline provides. Escaline free base carries the same active molecule but exhibits limited water solubility and different physical handling characteristics. Escaline Hydrochloride stands apart because it offers a proven combination: well-defined ethoxy substitution occupying the precise middle position in the linear alkoxy series, confirmed hydrochloride salt form, improved metabolic stability over mescaline, consistent potency values across studies, excellent aqueous solubility, and a physical profile well-suited for long-term storage and accurate solution preparation. That reliability is why researchers specifically seek to buy Escaline Hydrochloride with bitcoin—transactions settle instantly without banking delays, your personal financial information remains protected, payments can be made from any country without cross-border restrictions or currency conversion fees, and blockchain confirmation provides immutable payment records for your purchasing and laboratory files. When you are looking for where to buy authentic Escaline Hydrochloride payable with bitcoin, prioritize suppliers who provide batch-specific certificates of analysis confirming active compound identity, independently verified HPLC purity, NMR confirmation of ethoxy substitution pattern, and verification of hydrochloride salt form alongside transparent cryptocurrency payment instructions and discreet shipping.
There are compelling reasons why ethoxy-substituted escaline in hydrochloride salt form is the preferred reference compound for chain-length relationship studies. The ethoxy group represents the standard two-carbon linear extension that separates the parent compound mescaline from the longer-chain analog proscaline—creating a definitive three-point reference scale where every structural difference is limited to a single predictable variable. The hydrochloride salt form, meanwhile, typically forms a highly crystalline solid with excellent aqueous solubility and consistent physical properties that simplify accurate dosing and stock solution preparation across an entire laboratory study. Buy premium-grade Escaline Hydrochloride with guaranteed purity, confirmed ethoxy substitution, and verified hydrochloride salt form, and your data remains comparable across laboratories and published reference values—with the added confidence that every assay began with identically characterized reference material whose solubility, purity, and structural identity are fully documented.

Proper Storage, Handling, and Research Applications

Even though escaline hydrochloride incorporates structural features that improve metabolic stability compared to mescaline, and the hydrochloride salt form typically exhibits excellent solid-state stability, proper storage remains essential to maintain full potency, preserve chemical integrity, and prevent degradation—especially important with phenethylamine salts, where oxidation, moisture, and light can alter stability over time regardless of counterion. You should store Escaline Hydrochloride in its original sealed container, protected from direct sunlight, excessive heat, moisture, and acidic or oxidizing conditions. The recommended storage temperature is between 15 and 25 degrees Celsius at room temperature; avoid leaving inventory in environments where the temperature exceeds 30 degrees Celsius or exposing it to sustained high humidity. Under recommended conditions, sealed hydrochloride salt inventory remains stable for at least 12 months with no measurable change in purity or biological activity. Once opened, minimize repeated exposure to air and moisture and keep the container tightly closed between uses. As with all potent serotonin receptor agonist research compounds—and particularly critical when working with purified phenethylamine hydrochloride salts—wear nitrile gloves, eye protection, and a lab coat; handle all material inside a certified fume hood; avoid accidental ingestion, inhalation, or contact with skin or mucous membranes; and dispose of waste according to institutional hazardous substance protocols. Escaline Hydrochloride is an investigational reference compound and potent serotonin 5-HT₂ receptor ligand, so it should be stored securely, handled only by trained personnel, and kept strictly isolated from unauthorized access. This product is intended exclusively for laboratory research, educational investigation, and pharmacological reference applications—particularly studies examining serotonin receptor function, phenethylamine structure-activity relationships, linear alkoxy chain-length effects, and salt-formulation influences on solubility and stability. It is not intended for consumption, prescription, or any clinical purpose. Always confirm local regulatory status before ordering.

Sourcing, Payment Options, and Frequently Asked Questions

Secure Purchasing and Bitcoin Payment Advantages

When you are ready to purchase Escaline Hydrochloride, selecting the right supplier and payment method is equally important—especially when ordering reference compounds where structural identity, salt form, and purity directly determine research validity. Paying with bitcoin offers distinct advantages for research purchasers: transactions complete within minutes without banking delays, your sensitive financial data is never shared with merchants, reducing identity theft risk, payments can be sent internationally without currency conversion fees or cross-border transfer limits, and irreversible blockchain confirmation eliminates chargeback fraud while providing permanent, immutable transaction records for your purchasing files. Many researchers specifically seek to buy Escaline Hydrochloride with bitcoin because it allows them to complete purchases securely from anywhere in the world, maintain financial privacy, and receive instant confirmation that speeds order processing and discreet shipping—particularly valuable when ordering reference compounds that require careful handling and secure packaging. When comparing suppliers to find the best price for Escaline Hydrochloride payable with bitcoin and discreet shipping, always verify specifications first—confirm the active compound CAS number, molecular formula, hydrochloride salt identity, and purity match authoritative values, and specifically request batch-specific analytical documentation including HPLC purity, NMR identity confirmation confirming the ethoxy substitution pattern, and verification of the hydrochloride salt form. Legitimate suppliers will provide these documents upon request. If a supplier cannot or will not share NMR confirmation of substitution pattern or salt-form verification, do not purchase—mass spectrometry alone cannot reliably distinguish Escaline from Mescaline or Proscaline, nor can it confirm which salt form you are receiving. Look for suppliers who clearly display cryptocurrency payment instructions, offer insured, trackable shipping with privacy-protected packaging, and do not require excessive personal information solely to process an order. Many people ask, “Can I buy authentic Escaline Hydrochloride with bitcoin and guaranteed identity and salt form?” and the answer is straightforward: verify the batch-specific analytical data, including independent NMR confirmation of ethoxy substitution and hydrochloride salt verification; confirm the supplier accepts cryptocurrency with transparent payment instructions; and always cross-reference specifications against public chemical databases before releasing payment.

Frequently Asked Questions

Is Escaline Hydrochloride the same compound as Mescaline, Proscaline, or Escaline free base?
No. Escaline Hydrochloride carries a 4-ethoxy group, distinguishing it from both Mescaline (4-methoxy) and Proscaline (4-propoxy). It contains the same active molecule as Escaline free base but as a hydrochloride salt with distinct physical properties, including improved water solubility. Always confirm identity through CAS 54851-35-1, NMR confirmation of ethoxy substitution, and separate verification of the hydrochloride counterion before ordering.
What purity and identity standards should I require for reliable research?
For valid experimental results, you should insist on at least 98% total purity verified by HPLC with identity confirmed by NMR spectroscopy capable of verifying the ethoxy substitution pattern and distinguishing it from shorter or longer alkoxy variants, plus separate verification confirming the hydrochloride salt form. Mass spectrometry alone cannot reliably distinguish Escaline from close structural analogs or identify salt form.
How potent is escaline hydrochloride compared to other phenethylamine analogs?
Escaline Hydrochloride exhibits significantly higher serotonin 5-HT₂A receptor affinity and functional potency compared to Mescaline, typically falling predictably between Mescaline and Proscaline in the linear alkoxy series. The hydrochloride counterion does not alter intrinsic pharmacological activity—potency values match other salt forms when compared on a molar free-base basis. Always verify exact structure through full spectroscopic verification before use.
Where can I buy authentic Escaline Hydrochloride that accepts bitcoin?
You should purchase from suppliers who provide full batch verification, including HPLC purity confirming ≥98% and NMR confirming the ethoxy substitution pattern, separate verification of the hydrochloride salt form, clearly display cryptocurrency payment instructions, and offer discreet shipping suitable for sensitive reference compounds. Always review batch certificates before placing an order.
How do I order Escaline Hydrochloride online securely using Bitcoin?
Select suppliers who protect your personal information, provide clear payment instructions and immutable transaction confirmation, offer insured shipping suitable for research compounds, and supply batch-specific Certificates of Analysis, including purity, identity, substitution confirmation, and salt-form verification. Retain your transaction ID for order tracking and laboratory record-keeping.
What research applications is Escaline Hydrochloride best suited for?
Escaline Hydrochloride is ideal for serotonin 5-HT₂ receptor binding and functional assays, phenethylamine structure-activity relationship studies quantifying linear alkoxy chain-length effects, salt-formulation research comparing solubility and stability across counter-ions, and comparative pharmacology where intermediate chain-length reference material is required.
What solvents dissolve Escaline Hydrochloride most effectively?
Escaline Hydrochloride exhibits excellent solubility in water and aqueous buffer solutions—a key advantage over the free base form—and excellent solubility in organic solvents including methanol, ethanol, DMSO, and acetonitrile. Prepare aqueous stock solutions as needed; hydrochloride salt dissolves readily without requiring organic co-solvents, but avoid strongly basic conditions that may convert the salt back to free base.
What storage conditions preserve potency and chemical integrity?
Store sealed at room temperature (15–25°C), protected from sunlight, heat, moisture, and oxidizing conditions. The hydrochloride form typically exhibits good stability, but avoid temperatures above 30°C or high humidity. Sealed inventory remains stable for at least 12 months under proper conditions; once opened, keep the container tightly closed and protected from moisture and light exposure.
Is escaline hydrochloride approved for human consumption or clinical use?
No. Escaline Hydrochloride is an investigational reference compound belonging to the alkoxy-substituted phenethylamine class. It has not been approved for clinical use anywhere, and it is supplied exclusively for laboratory research, educational investigation, and pharmacological reference applications—particularly studies examining serotonin receptor function, phenethylamine structure-activity relationships, and substitution pattern effects. It is not intended for consumption, prescription, or any clinical purpose. Always confirm local regulatory status before ordering.
Why choose escaline hydrochloride over other analogs or salt forms?
Escaline Hydrochloride combines the definitive intermediate ethoxy substitution—creating the essential reference point between mescaline and proscaline—with a hydrochloride salt form valued for excellent aqueous solubility and consistent dosing. It serves as both the benchmark ethoxy-substituted reference standard and a reliable hydrochloride salt for comparative formulation studies. Always verify both substitution pattern and salt identity by NMR before use.
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Reputable suppliers accepting bitcoin offer discreet shipping options with plain, protective packaging suitable for phenethylamine hydrochloride reference compounds, insured tracking, and privacy-protected delivery. Always confirm shipping terms and packaging standards before ordering, and ensure your laboratory holds all necessary authorizations to receive research reference material in your location.

Final Summary

In summary, escaline hydrochloride represents an essential reference compound in modern serotonin receptor pharmacology, phenethylamine structure-activity research, and salt-formulation studies—combining a precisely defined ethoxy substitution occupying the definitive middle position in the linear alkoxy series, confirmed hydrochloride salt form, improved metabolic stability over mescaline, excellent aqueous solubility, and predictably enhanced 5-HT₂A receptor affinity compared to the parent compound. Whether you seek to order Escaline Hydrochloride online using bitcoin for fast, private settlement and secure delivery, are looking for premium grade material with guaranteed purity, confirmed ethoxy substitution, and verified hydrochloride salt form for receptor binding, functional activity, formulation, or comparative pharmacology research, want competitive pricing payable with cryptocurrency for ongoing research programs requiring consistent reference standards, or simply need to know where to buy authentic Escaline Hydrochloride with discreet shipping and flexible payment options — the principles remain consistent: verify active compound identity through authoritative public databases including the correct CAS number and molecular specifications, demand batch-specific analytical verification including HPLC purity, NMR identity confirmation confirming ethoxy substitution pattern, and separate verification of hydrochloride salt form, purchase from suppliers who offer transparent cryptocurrency payment instructions and reliable shipping suitable for potent reference compounds, and always prioritize verified structural identity, confirmed salt form, and documented purity over prices that appear too good to be true. Your research conclusions are only as reliable as the reference materials you use—and in serotonin receptor pharmacology, phenethylamine structure-activity studies, and alkoxy chain-length research, confirmed substitution pattern, verified salt form, and known position within the homologous series are everything. That is why more researchers choose Escaline Hydrochloride and bitcoin: a well-characterized intermediate reference compound, independently verified hydrochloride quality, superior solubility, secure payment, and permanent confirmation. Sometimes the most valuable research improvement is simply selecting the right reference compound—one verified ethoxy substitution, one confirmed salt form, and one secure payment method that works worldwide.
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